* Born on Nov. 23, 1967 in Cape Town.

PLAYING CAREER

* Made his test debut against Australia in Melbourne in 1993 and went on to play 101 tests, amassing 7,289 runs, including 21 centuries, at an average of 45.27.

* A gritty left-handed batsman, played his last test against New Zealand in Wellington in 2005.

* Batted for more than 14 hours to hit his test-highest score of 275 against England at Kingsmead in 1999-2000.

* Made his one day international debut against Australia in Sydney in 1993 and totalled 6,798 runs, including 13 tons, from 185 ODIs at an average of 40.95.

* His last ODI appearance was against Sri Lanka in Durban in 2003.

* His highest ODI score of 188 not out against United Arab Emirates in the 1996 World Cup is still the highest individual score by a South African batsman in 50-over cricket.

* Half-brother Peter Kirsten played 12 tests and 40 ODIs for South Africa.

COACHING CAREER:

* Post-retirement, had a brief stint as the Warriors' batting consultant before setting up his own academy in Cape Town in 2006.

* Signed as India coach in late 2007 but took charge in early 2008. Went on to guide them to the top of the test rankings and the 2011 ODI World Cup victory after which he stepped down.

* Took over as South Africa coach in 2011 on a two-year deal with option to renew it for another couple of years. Oversaw the team's rise to the top of the test rankings in 2012.

* Announced on May 10 2013 that he would leave the South African post after June's Champions Trophy, citing family reasons.(Compiled by Amlan Chakraborty in New Delhi, editing by Clare Fallon)

[More from BGR: ]

This article was

LONDON (Reuters) - British scientists are stepping up clinical tests of gene therapy in a bid to help people with advanced heart failure pump blood more efficiently.

Researchers said on Tuesday they planned to enroll patients into two new clinical trials using Mydicar, a gene therapy treatment made by privately held U.S. biotech company Celladon.

After more than 20 years of research, the ground-breaking method for fixing faulty genes is starting to deliver, with European authorities approving the first gene therapy for an rare metabolic disease last November.

In the case of heart failure, the aim is to insert a gene called SERCA2a directly into heart cells using a modified virus, delivered via a catheter infusion. Lack of SERCA2a leads to ever weaker pumping in people with heart failure.

Although drugs offer some relief, there is currently no way of restoring heart function and the prognosis for those with advanced disease is worse than for many cancers.

One of the studies, led by scientists at Imperial College London, is part of a wider mid-stage Phase II project sponsored by Celladon that involves 200 patients worldwide, some of whom have already been treated in the United States and Denmark.

The second trial, which is due to start in the summer, will test the same treatment in 24 British patients already fitted with mechanical heart pumps to see how the approach may help in this particular setting.

It promises to be a long haul, with extensive Phase III studies still needed once results of the current mid-stage tests are received, which Celladon expects in the first half of 2015.

Gene therapy has experienced a series of advances and setbacks over the decades. The most notable blow came in 1999 when an Arizona teenager died in a gene therapy experiment. More recent results, however, have been promising in fields ranging from immune system diseases to blindness.

"It is a great example of the slow burn of good laboratory science translating into a potential clinical treatment," said Peter Weissberg, medical director of the British Heart Foundation, which is co-funding the second trial.

Because gene therapy replaces or boosts the activity of a faulty gene, it offers the possibility of a one-time "fix" - and that creates an economic challenge.

Any gene therapy is bound to be expensive, since a single dose could last a lifetime and the manufacturer will have just one shot at recouping its investment.

But Alexander Lyon of Imperial College, lead investigator on both studies, said it could be a cost-effective solution in heart failure if it avoided the need for interventions such as heart transplants at 200,000 pounds ($300,000) each.

($1 = 0.6455 British pounds)

(Reporting by Ben Hirschler; editing by Patrick Graham)

SEOUL (Reuters) - When romantic actress Lee Si-young swapped her glamorous roles in South Korean dramas for boxing gloves in a bid to win an Olympic medal, her victories triggered a storm of protest that has marred her unexpected success in the ring.

The 31-year-old, better known for her roles in TV shows such as "Wild Romance" and "Boys Before Flowers", had tears of joy in her eyes when she defeated 19-year-old Kim Da-som by 22 points to 20 in the 48 kg (106 lb) class at the South Korean national team tryouts in late April.

Her win, however, triggered a bitter battle in which the Korean Amateur Boxing Federation (KABF) was accused of giving Lee an unfair advantage in a bid to use her celebrity status to boost its fan base at the expense of the sweat and passion of her relatively unknown opponent.

"The match was preposterously biased - if the umpire gave Lee Si-young's slaps on the wrist 22 points, then Kim should have been given at least 50 points," Byun Hee-jae, a conservative political commentator and a self-proclaimed boxing fan, said on his twitter feed.

"This country has gone so crazy that being pretty gets more points even in boxing."

The boxing federation, though, said that selecting who is going to represent the nation cannot be manipulated or bribed.

"Play the video and you will see that Kim scored less valid punches than Lee. Lee's face is quite clean - no major bruises or swelling. She even went out for photo shooting two days after the match," said KABF senior manager Choi Hee-kuk.

Lee, who has been boxing since 2010, and her manager declined to comment, despite multiple attempts to contact them. They referred inquiries to officials at the Incheon City Boxing club, where she is a member.

"She (Lee) tried hard, fought well and won. If people think she won because she is pretty, then this is rather a reverse discrimination against her," said Oh Jeong-kyu, assistant manager at the Incheon club.

Internet opinion was divided, with some instead rooting for Lee. "I cried reading her story. She is very beautiful and passionate," said Marcella Kim on Twitter.

Whether Lee could actually represent her country depends on her bulking up, since neither the Olympics nor the Asian Games have anything lighter than a 51 kg (112 lb) class for women's boxing. She has said she intends to do so.

(Reporting By Narae Kim; Editing by Elaine Lies)

The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) will be released in May. Yahoo is featuring first-person stories from Americans who are diagnosed with some of the most common mental health disorders in the United States. Here's one story.

FIRST PERSON | When I was 16, smoking pot and drinking cases of beer were my medication for ADHD -- although I didn't know that's what I had at the time. From what I could tell, ADHD diagnostics didn't commonly exist when I was in high school.

All my friends drank beer and smoked pot. Here in the desert of Midland, Texas, there's practically nothing to do but drink and hit house parties. In school, I could not sit in class and could not understand my assignments, and when there was too much distraction, my mind floated away. I was a straight-A student until I started missing class, and I had high anxiety after that. Throughout my early 20s and 30s, this chaos impacted my work, friends and relationships.

I attended treatment facilities and psychiatric hospitals. Each would make a fresh diagnosis: alcoholism, substance abuse, schizophrenia and bi-polar disorder. I was baffled as to my condition and in turmoil over what would be diagnosed next. When I was 35, after three stints in mental institutions and four in drug rehabilitation centers, I was diagnosed as an adult with ADHD.

I went to a neurologist in Midland, and he asked several questions and included my drug problem and alcohol abuse. He asked if I heard of ADHD. I thought this was a child's problem, I informed him. He gave me a new prescription of Adderall. Finally, at 44, I was sober and taking my medication as prescribed. Since then, I haven't drank or done drugs.

Now at 50, my whole view of life is different. I had to start my life anew, but now, financially and mentally, I'm OK, and I think my life will remain stable. I had to learn how to cope with my new life. I am able to collect my thoughts, and my anxieties are few. My religious belief is strong. My faith in God and prayer is a daily habit for me. (My religious beliefs in God have been with me since childhood, but faith alone in the early years was unlikely to overcome addiction.)

I do understand that I am taking chances with Adderall, which is addictive. But my spiritual recovery is how I live. The medicine is just an aid to help.

The top 20 movies at U.S. and Canadian theaters Friday through Sunday, followed by distribution studio, gross, number of theater locations, average receipts per location, total gross and number of weeks in release, as compiled Monday by Hollywood.com are:

1. "Iron Man 3," Disney, $174,144,585, 4,253 locations, $40,946 average, $174,144,585, one week.

2. "Pain & Gain," Paramount, $7,511,315, 3,287 locations, $2,285 average, $33,830,390, two weeks.

3. "42," Warner Bros., $6,055,327, 3,345 locations, $1,810 average, $78,181,097, four weeks.

4. "Oblivion," Universal, $5,642,335, 3,430 locations, $1,645 average, $75,814,250, three weeks.

5. "The Croods," Fox, $4,202,639, 2,915 locations, $1,442 average, $168,720,798, seven weeks.

6. "The Big Wedding," Lionsgate, $3,881,857, 2,633 locations, $1,474 average, $14,216,422, two weeks.

7. "Mud," Roadside Attractions, $2,160,319, 576 locations, $3,751 average, $5,168,217, two weeks.

8. "Oz the Great and Powerful," Disney, $2,113,009, 1,160 locations, $1,822 average, $228,858,941, nine weeks.

9. "Scary Movie 5," Weinstein Co., $1,441,360, 1,857 locations, $776 average, $29,609,668, four weeks.

10. "The Place Beyond the Pines," Focus, $1,280,152, 1,162 locations, $1,102 average, $18,676,792, six weeks.

11. "G.I. Joe: Retaliation," Paramount, $1,270,094, 1,804 locations, $704 average, $118,752,410, six weeks.

12. "Olympus Has Fallen," FilmDistrict, $1,194,650, 1,632 locations, $732 average, $95,374,529, seven weeks.

13. "Jurassic Park" in 3-D, Universal, $896,750, 980 locations, $915 average, $43,756,735, five weeks.

14. "The Company You Keep," Sony Pictures Classics, $703,465, 541 locations, $1,300 average, $3,433,182, five weeks.

15. "Evil Dead," Sony, $614,524, 959 locations, $641 average, $53,200,013, five weeks.

16. "Tyler Perry's Temptation," Lionsgate, $411,592, 504 locations, $817 average, $51,365,503, six weeks.

17. "Jack the Giant Slayer," Warner Bros., $295,425, 335 locations, $882 average, $64,151,565, 10 weeks.

18. "Disconnect," LD Entertainment, $210,744, 161 locations, $1,309 average, $1,054,974, four weeks.

19. "Identity Thief," Universal, $204,010, 300 locations, $680 average, $133,454,405, 13 weeks.

20. "Silver Linings Playbook," Weinstein Co., $198,548, 468 locations, $424 average, $131,703,512, 25 weeks.

___

Online:

http://www.hollywood.com

___

Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

(Reuters) - Business software maker BMC Software Inc, whose anemic growth has been a source of frustration for its largest shareholder, said it would be taken private by a group led by Bain Capital and Golden Gate Capital for about $6.9 billion.

Elliott Management, which owns 9.6 percent of BMC and had been pushing for a sale for more than a year, had argued that BMC's management was neglecting the huge opportunity to expand into the fast-growing cloud computing market.

"Going private will be very positive for them because it will enable them to make the changes that were necessary, that were much difficult when you are a public company," Lazard Capital Markets analyst Joel Fishbein said.

BMC has some catching up to do in a market now dominated by Salesforce.com Inc and where Oracle Corp, SAP AG and Microsoft Corp are investing heavily.

BMC's revenue is expected to have grown just 3 percent in the year ended March 31 to $2.23 billion, after growth of just 5 percent the previous year. BMC reports fourth-quarter results on Tuesday.

The deal represents this year's largest "pure" leveraged buyout so far.

Michael Dell has teamed up with private equity firm Silver Lake to take Dell Inc private for $24.4 billion, yet that buyout firm accounts for only a quarter of the equity in the deal. Earlier this year, Warren Buffett agreed to buy ketchup maker Heinz for $23 billion with private equity firm 3G Capital being a minority investor.

In BMC, private equity saw a company with stable cash flows and a lot of potential to leverage. The company has net debt of just $151 million, according to Thomson Reuters data.

Elliott, Paul Singer's activist hedge fund, succeeded in adding two directors to BMC's board last year after a proxy battle.

The hedge fund firm, founded by the billionaire Singer in 1977, had also criticized BMC's "ineffective" merger and acquisition strategy, arguing the company took too long to make acquisitions and paid too much.

The offer price of $46.25 per share represents a premium of less than 2 percent to BMC's Friday close of $45.42.

Elliott will make about a 20 percent return on its initial investments in BMC. It first bought shares of the company in early 2012 in the high $30s, and started agitating for a sale of the company in May of that year.

The stock has risen 4.5 percent since March 21, when Reuters reported that private equity groups were looking to buy the company.

BMC shares were trading at $45.50, up 8 cents, by midday on the Nasdaq.

STREAMLINING

BMC has two main divisions. The enterprise services management business manages networks, databases and storage and brings in nearly two-thirds of total revenue, but has stagnated over the years.

The mainframe services management unit, which helps automate data center operations, has grown slowly but is a cash cow that could help the new owners maximize profits.

The private equity group also includes GIC Special Investments Pte Ltd, part of Singapore's sovereign wealth fund, and Insight Venture Partners, a New York investment firm that focuses on software and internet businesses.

"I think they will streamline the business, focus on the higher growth areas, either divest or spin off some of the unproductive businesses," Fishbein said, adding that he expects it will take 12-18 months to "right-size" the business.

Under the sale agreement, Houston-based BMC has a "go-shop" provision that allows it to seek alternative proposals within 30 days. Analysts said it was unlikely BMC would get better offers.

BMC, which also competes with CA Inc and Compuware Corp, said the deal is expected to close later this year. Credit Suisse, RBC Capital Markets and Barclays have agreed to provide debt financing for the deal.

Morgan Stanley & Co LLC and BofA Merrill Lynch were financial advisers to BMC, while Wachtell, Lipton, Rosen & Katz was legal counsel.

Qatalyst Partners, Credit Suisse, RBC Capital Markets and Barclays served as financial advisers to the buyers, while Kirkland & Ellis LLP acted as legal counsel.

Sidley Austin LLP was legal adviser to GIC and Willkie Farr & Gallager LLP was legal adviser for Insight Venture Partners. Moelis & Co advised Elliott Management.

(This version of the story corrects paragraph 23 to show Moelis advised Elliott, not BMC.)

(Additional reporting by Supantha Mukherjee and Aditya Kondalamahanty in Bangalore, Nicola Leske, Nadia Damouni and Greg Roumeliotis in New York; Editing by Saumyadeb Chakrabarty and Marguerita Choy)

The KC-135 plane crashed Friday afternoon about 100 miles (160 kilometers) west of the air base that the U.S. operates in Kyrgyzstan to support military operations in Afghanistan.

Officials at the U.S. Transit Center at the Manas base have released no information yet on the cause of the crash and could not immediately be reached on Saturday for any further information.

Emergencies Minister Kubatbek Boronov told The Associated Press that Kyrgyz search teams found the two fragmented bodies Saturday morning and they have not yet been identified. He said the Kyrgyz rescuers were working with U.S. military personnel from Manas to search for the third crewman and the flight recorders.

Dozens of U.S. military personnel scoured the area on Saturday and set up a security cordon around the crash site.

Parts of the plane were scattered across a wide area near the village of Chaldovar. Some pieces, including the tail, came down in a grassy valley bordered by steep mountains, but others landed in spots much more difficult for search teams to reach.

Residents of the rural, sheep-herding region described hearing the plane explode in the air and seeing it break apart as it fell.

"I heard a very loud explosion," Emil Bokochev, a member of the village council, told an AP reporter at the site. "Literally six or seven seconds afterward there was another explosion and the plane broke apart into four or five pieces and at that moment we thought it was going to fall on the village Chaldovar."

The plane was on a refueling mission for Afghanistan war operations at the time of the crash, a U.S. defense official in Washington said, speaking anonymously because he was not authorized to discuss the details of an ongoing investigation.

The U.S. base, which is adjacent to Manas International Airport outside Bishkek, the Kyrgyz capital, was established in late 2001 to support the international military campaign in Afghanistan. It functions as an interim point for troops going into or out of Afghanistan and as a home for the tanker planes that refuel warplanes in flight.

The Manas base has been the subject of a contentious dispute between the United States and its host nation.

In 2009, the U.S. reached an agreement with the Kyrgyz government to use it in return for $60 million a year. But the lease runs out in June 2014, and the U.S. wants to keep the base longer to aid in the withdrawal of troops from Afghanistan. Kyrgyzstan is reluctant to extend the lease.

_____

AP writers Dalton Bennett in Chaldovar, Kyrgyzstan, and Robert Burns in Washington, D.C., contributed to this report.

The politically volatile debate reflects a reality that's difficult for parents, including the president, to swallow: Quite a number of teenagers have sex. So how easily should they be able to get a pill that prevents pregnancy if taken soon enough after sex?

On Tuesday, the Food and Drug Administration made it a little easier, saying anyone 15 or older could begin buying one brand, Plan B One-Step, without a prescription two years younger than the current age limit of 17 and that the pill no longer has to be locked behind pharmacy counters.

But it's far from clear whether that will happen. U.S. District Judge Edward Korman of New York had given the FDA until Monday to lift all age limits on Plan B and a cheaper generic, mandating that emergency contraception be sold just like aspirin. Instead, by requiring that buyers prove their age at the cash register, the FDA decided to treat it like beer.

The Justice Department hasn't said whether it will appeal Korman's order and thus back FDA's new approach, and that leaves the whole issue in limbo.

"This is a truly bizarre and unprecedented situation," said American University law professor Lewis A. Grossman, a specialist in food and drug law.

On Wednesday, doctors' groups, led by the American College of Obstetricians and Gynecologists, urged the Obama administration not to let the FDA action be the last word.

Any over-the-counter access marks a long-awaited change, but it's not enough, said Dr. Cora Breuner of the American Academy of Pediatrics, which supports nonprescription sale of the morning-after pill for all ages.

"We still have the major issue, which is our teen pregnancy rate is still too high," Breuner said.

Even though few young girls likely would use Plan B, which costs about $50 for a single pill, "we know that it is safe for those under 15," she said.

Most 17- to 19-year-olds are sexually active, and 30 percent of 15- and 16-year-olds have had sex, according to a study published last month by the journal Pediatrics. Sex is much rarer among younger teens. Likewise, older teens have a higher pregnancy rate, but that study also counted more than 110,000 pregnancies among 15- and 16-year-olds in 2008 alone.

The White House sought Wednesday to put much as much distance as possible between President Barack Obama and this political hot potato.

"The president, the White House, did not weigh in on this decision," White House spokesman Jay Carney said of the FDA's move.

Obama must balance his own instincts as the father of two school-age daughters with the wishes of numerous political constituencies, including women's groups whose influence runs deep within the Democratic Party. It was just last week that Obama became the first president to address Planned Parenthood in person, telling the abortion rights group that as long as women must fight to make their own health choices, "you've also got a president who's going to be right there with you fighting every step of the way."

Contraception advocates see a double standard. No one is carded when buying a condom, but under the FDA's decision they would have to prove their age when buying a pill to prevent pregnancy if that condom breaks.

"This isn't a compromise. This is wrong," said Cynthia Pearson of the National Women's Health Network.

Likewise, social conservatives were outraged by the FDA's move, saying it was important for parents and medical professionals to be involved in such decisions involving teens.

"This decision undermines the right of parents to make important health decisions for their young daughters," said Anna Higgins of the Family Research Council. She added that removing the prescription requirement meant "teens and women will avoid necessary medical screenings" that could detect serious problems.

The FDA had been poised to lift all age limits and let Plan B sell over the counter in late 2011, when Health and Human Services Secretary Kathleen Sebelius, in an unprecedented move, overruled her own scientists. Sebelius said some girls as young as 11 were physically capable of bearing children but shouldn't be able to buy the pregnancy-preventing pill on their own.

Ruling earlier this month in a lawsuit challenging that decision, Korman blasted the Obama administration for letting election-year politics trump science. The judge called the morning-after pill "among the safest drugs sold over the counter," and gave the government 30 days to lift all age limits.

Obama aides bristled at the suggestion that the FDA decision was an attempt at political compromise, insisting the FDA merely responded to an application filed by Plan B's manufacturer which sought the 15 age limit and over-the-counter sales.

At the same time, Carney signaled that a policy allowing 15-year-olds to buy the pill off the shelf would be more palatable to Obama than the prospect of 11-year-olds having unfettered access. Pointing to Obama's comments in support of Sebelius back in 2011, Carney said, "he referred to younger girls, and I believe so did Secretary Sebelius."

If a woman already is pregnant, the morning-after pill has no effect. It prevents ovulation or fertilization of an egg. According to the medical definition, pregnancy doesn't begin until a fertilized egg implants itself into the wall of the uterus. Still, some critics say Plan B is the equivalent of an abortion pill because it may also be able to prevent a fertilized egg from attaching to the uterus, a contention that many scientists and Korman, in his ruling said has been discredited.

WASHINGTON (Reuters) - Hillary Clinton, already the front-runner in the minds of many Democrats for the 2016 U.S. presidential election, is writing a memoir about world affairs and her time as secretary of state that will likely fuel more speculation about her political future.

The presidential prospects of Clinton, the wife of former President Bill Clinton, are a subject of feverish speculation in Washington and elsewhere as Democrats look to see over the horizon past President Barack Obama.

The book, her fifth, is to be published next year, and a tour to promote the memoir in 2014 would serve only to generate more guessing about her plans for 2016.

Her inner circle insists Clinton has made no decision one way or the other. This has not stopped the formation of a "Ready for Hillary" political action committee to promote her potential candidacy and seek volunteers and monetary contributions.

Among the subjects Clinton will explore are the killing of Osama Bin Laden, the overthrow of the Qaddafi regime in Libya, the situations in Iraq and Afghanistan, the Arab Spring, diplomacy pertaining to Iran and North Korea and relations with U.S. allies.

"Hillary Clinton's extraordinary public service has given her a unique perspective on recent history and the challenges we face," said Jonathan Karp, president and publisher of the Simon & Schuster Publishing Group who will edit Clinton's as-yet untitled book.

The book will also address trends in economics, energy and climate change, democracy and human rights, the critical role of women and girls, technology and innovation and health and human development, Simon & Schuster said on Thursday.

When she left the State Department February 1, Clinton, 66, had been suffering from a blood clot near her brain. She said she needed some time to rest and to settle on ways she can help women and children in the United States and around the world.

She is now re-emerging. Last month she announced that she now supports marriage rights for gay Americans. Back when she ran for the Democratic presidential nomination in 2008 she had backed civil unions for gay couples.

On Tuesday night in Washington, she spoke about global women's rights at an event held by the non-governmental organization Vital Voices, sharing the stage with a potential 2016 rival, Vice President Joe Biden.

She will give her first paid speech in Dallas on April 24, the day before she attends ceremonies there marking the opening of George W. Bush's presidential library.

Polls show Clinton as the runaway frontrunner at this stage among Democrats for their party's 2016 presidential nomination and that she leads all potential Republican contenders, including former Florida Governor Jeb Bush, Florida Senator Marco Rubio and New Jersey Governor Chris Christie.

(Additional reporting by Chris Michaud in New York and Susan Heavey in Washington; editing by Jackie Frank)